Pada pria, lingkar pinggang (LP) >=120cm menghadapi risiko kematian dua kali lebih besar dibanding LP <90.
Pada wanita LP >=110cm menghadapi risiko kematian dua kali lebih besar dibanding LP <75cm.
LP semakin besar akan meningkatkan risiko kematian.
Waist Circumference and All-Cause Mortality in a Large US Cohort
Eric J. Jacobs, PhD; Christina C. Newton, MSPH; Yiting Wang, PhD; Alpa V. Patel, PhD; Marjorie L. McCullough, ScD;Peter T. Campbell, PhD; Michael J. Thun, MD; Susan M. Gapstur, PhD
Arch Intern Med. 2010;170(15):1293-1301. doi:10.1001/archinternmed.2010.201
Arch Intern Med. 2010;170(15):1293-1301. doi:10.1001/archinternmed.2010.201
Background Waist circumference (WC), a measure of abdominal obesity, is associated with higher mortality independent of body mass index (BMI). Less is known about the association between WC and mortality within categories of BMI or for the very high levels of WC that are now common.
Methods We examined the association between WC and mortality among 48 500 men and 56 343 women, 50 years or older, in the Cancer Prevention Study II Nutrition Cohort. A total of 9315 men and 5332 women died between 1997 and the end of follow-up in 2006.
Results After adjustment for BMI and other risk factors, very high levels of WC were associated with an approximately2-fold higher risk of mortality in men and women (among men, relative risk [RR] = 2.02; 95% confidence interval [CI], 1.71-2.39 for WC >=120 cm compared with <90 cm; among women, RR = 2.36; 95% CI, 1.98-2.82 for WC >=110 cmcompared with <75 cm). The WC was positively associated with mortality within all categories of BMI. In men, a 10-cm increase in WC was associated with RRs of 1.16 (95% CI, 1.09-1.23), 1.18 (95% CI, 1.12-1.24), and 1.21 (95% CI, 1.13-1.30) within normal (18.5 to <25), overweight (25 to <30), and obese (>=30) BMI categories, respectively. In women, corresponding RRs were 1.25 (95% CI, 1.18-1.32), 1.15 (95% CI, 1.08-1.22), and 1.13 (95% CI, 1.06-1.20).
Conclusion These results emphasize the importance of WC as a risk factor for mortality in older adults, regardless ofBMI.
Methods We examined the association between WC and mortality among 48 500 men and 56 343 women, 50 years or older, in the Cancer Prevention Study II Nutrition Cohort. A total of 9315 men and 5332 women died between 1997 and the end of follow-up in 2006.
Results After adjustment for BMI and other risk factors, very high levels of WC were associated with an approximately2-fold higher risk of mortality in men and women (among men, relative risk [RR] = 2.02; 95% confidence interval [CI], 1.71-2.39 for WC >=120 cm compared with <90 cm; among women, RR = 2.36; 95% CI, 1.98-2.82 for WC >=110 cmcompared with <75 cm). The WC was positively associated with mortality within all categories of BMI. In men, a 10-cm increase in WC was associated with RRs of 1.16 (95% CI, 1.09-1.23), 1.18 (95% CI, 1.12-1.24), and 1.21 (95% CI, 1.13-1.30) within normal (18.5 to <25), overweight (25 to <30), and obese (>=30) BMI categories, respectively. In women, corresponding RRs were 1.25 (95% CI, 1.18-1.32), 1.15 (95% CI, 1.08-1.22), and 1.13 (95% CI, 1.06-1.20).
Conclusion These results emphasize the importance of WC as a risk factor for mortality in older adults, regardless ofBMI.
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